BDBM50028091 (1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime::CHEMBL814::FLUVOXAMINE

SMILES COCCCC\C(=N/OCCN)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=CJOFXWAVKWHTFT-XSFVSMFZSA-N

Data  56 KI  12 IC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028091   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50028091((1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan...)Copy SMILESCopy InChI

Affinity DataIC50:  3.94E+4nMAssay Description:Inhibition of sodium current measured using whole-cell patch clamp experiments in HEK-293 cells stably transfected with hNaV1.5 cDNAMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLMCE
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI